Prognostic factors in soft tissue sarcoma Population - based studies on comorbidity , biomarkers , and methodological aspects

I. Maretty-Nielsen K, Aggerholm-Pedersen N, Keller J, Safwat A, Baerentzen S, Pedersen AB. Population-based Aarhus Sarcoma Registry: validity, completeness, and incidence of bone and soft tissue sarcomas in western Denmark. Clinical Epidemiology 2013; 5: 45–56 II. Maretty-Nielsen K, Aggerholm-Pedersen N, Safwat A, Jørgensen PH, Hansen BH, Baerentzen S, Pedersen AB, Keller J. Prognostic factors for local recurrence and mortality in adult soft tissue sarcoma of the extremities and trunk wall: a population-based cohort study of 922 consecutive patients. Acta Orthopaedica 2014; 85(3): 323-32 III. Maretty-Nielsen K, Aggerholm-Pedersen N, Safwat A, Baerentzen S, Pedersen AB, Keller J. Prevalence and prognostic impact of comorbidity in soft tissue sarcoma: a population-based cohort study. Acta Oncologica 2014; 53(9): 1188-96 IV. Maretty-Nielsen K, Aggerholm-Pedersen N, Keller J, Pedersen AB, Baerentzen S, Safwat A. Pretreatment biomarkers as prognosticators for survival in adult patients with non-metastatic soft tissue sarcoma: Does adjustment for comorbidity change the picture? Submitted V. Maretty-Nielsen K, Aggerholm-Pedersen N, Keller J, Safwat A, Baerentzen S, Pedersen AB. Relative mortality in soft tissue sarcoma patients: a Danish populationbased cohort study. BMC Cancer 2014; 14: 682 ABBREVIATIONS ASR Aarhus Sarcoma Registry CDR Danish Cause of Death Registry CI Confidence interval COD Cause of death CPR Civil personal registration CRP C-reactive protein CT Computed tomography DAG Directed acyclic graph DCR Danish Cancer Registry GIST Gastrointestinal stromal tumor Gy Gray HR Hazard ratio ICD International Classification of Diseases ICD-O ICD for Oncology IR Incidence rate IRR Incidence rate ratio MFH Malignant fibrous histiocytoma MR Mortality rate MRI Magnetic resonance imaging MRR Mortality rate ratio NLR Neutrophil to lymphocyte ratio NPR National Patient Registry NPU Nomenclature, Properties and Units RM Relative mortality RMR Relative mortality rate STS Soft tissue sarcoma WHO World Health Organization